Search on: CHOLINESTERASE INHIBITORS 
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Descriptor English:   Cholinesterase Inhibitors 
Descriptor Spanish:   Inhibidores de la Colinesterasa 
Descriptor Portuguese:   Inibidores da Colinesterase 
Synonyms English:   Anti-Cholinesterases
Anticholinesterase Drugs
Anticholinesterases
Cholinesterase Inhibitors, Irreversible
Cholinesterase Inhibitors, Reversible
Agents, Anticholinesterase
Anti Cholinesterases
Drugs, Anticholinesterase
Inhibitors, Acetylcholinesterase
Inhibitors, Cholinesterase
Inhibitors, Irreversible Cholinesterase
Inhibitors, Reversible Cholinesterase
Irreversible Cholinesterase Inhibitors
Reversible Cholinesterase Inhibitors
Acetylcholinesterase Inhibitors
Anticholinesterase Agents  
Tree Number:   D27.505.519.389.275
D27.505.519.625.120.300
D27.505.696.577.120.300
Definition English:   Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system. 
Indexing Annotation English:   DF: CHOLINESTERASE INHIB
See Related English:   Insecticides
 
History Note English:   65; CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE were see under CHOLINESTERASE INHIBITORS 1975-83, were Prov 1971-74; CHOLINESTERASE INHIBITORS, ORGANIC was see PHOSPHORUS POISONS, ORGANIC 1963-64 (PHOSPHORUS POISONS, ORGANIC deleted 1965) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   2850 
Unique Identifier:   D002800 

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